Notes:

He was slain by Hugh Campbell, Sheriff of Ayr at the instigation of Sir James Hamilton.
He succeeded as 2nd Earl of Cassillis in 1513. He was a prominent figure in the history of Scotland; Ambassador to England, a Privy-Councillor to James V, concluded truce with the Duke of Norfolk on part of Henry VIII after 1513.
He was invested as a Privy Counsellor (P.C.) [Scotland] to King James V. In 1525 he was tried for the murder of Martin Kennedy of Lochland in 1525, but was acquitted through the influence of his brother-in-law, the Earl of Argyll. In December 1526 he was a prisoner in the hands of the Douglas faction, after having joined the unsuccessful attempt of the Earl of Arran to rescue the young King James V. (http://www.thepeerage.com/p1224.htm#i24462)
Children:
Gilbert, 3rd Earl of Cassillis, m. Margaret Kennedy; b. between 1517 and 1518.
Thomas.
David of Culzean; m. Janet Kennedy, daughter of Duncan Kennedy of Daljedburgh.
Quintin, Abbot of Crossraguel who disputed three days at Maybole with Knox.
Archibald.
Hugh of Barquhany.
James of Uchtrelure.
(--?--); m. Thomas McClelland of Bombay.

Gilbert married Isabel CAMPBELL before 1513. Isabel was born about 1489; died after 1529. [Group Sheet] [Family Chart]

Notes:

He was educated at St. Andrews University, St. Andrews, Fife, Scotland. At Paris, France, he studied under the celebrated George Buchanan. On 6 February 1540/41 he had a charter of the Fief of Cassillis. On 24 November 1542 at Solway Moss, he was taken prisoner by the English. He became a Protestant, and went over to the English Party. In February 1545 he was released. He held the office of Extraordinary Lord of Session [Scotland] between 1546 and 1558. He fought in the Battle of Pinkie on 10 September 1547, where the Scots were defeated. He held the office of High Treasurer [Scotland] in 1554. (http://www.thepeerage.com/p5417.htm)
He succeeded as 3rd Earl of Cassillis. William Kennedy, Abbot of Crossraguel, was his guardian for eleven years. He was at the University of St. Andrew's in 1527; afterwards, he completed his education in Paris, remaining there until 1537. Was considered to be of excellent disposition and promising talents. He had many charters; when taken prisoner Solway Moss by the English, he was committed to Archbishop Cranmer, 1542, because he was an Anglican. Henry VIII loaded him with gifts. He was high Treasurer of Scotland, Chief Commander in the Army which attacked Berwick and invaded England 1557. He was sent to France to negotiate Queen Mary's marriage with the Dauphin, but met mysterious death (suspected poison) at Dieppe in 1558; buried at Maybole. The Earl married Margaret, daughter of Alexander Kennedy of Bargany in 1527.
Children:
Gilbert, fourth Earl of Cassillis, ancestor of the fifth, sixth, seventh and eighth Earls of Cassillis.
Hon. Sir Thomas of Culzean, m. Elizabeth McGill.
Lady Jean; m. Robert (--?--) Earl of Orkney.
Lady Catherine; m. Sir Patrick Vaus.

Gilbert married Margaret KENNEDY in 1540. Margaret was born about 1517 in Bargany, Dailly, Ayrshire, Scotland. [Group Sheet] [Family Chart]

Notes:

He was Master of Cassillis of Culzean, ancestor of the ninth Earl of Cassillis.
Children:
Thomas; d; died unmarried.
James, succeeded to Culzean.
Sir Alexander of Craigoch, m. Agnes Kennedy.
David of Garrihorn.
Margaret.
Helen.
Susanna.

Thomas married Elizabeth MCGILL about 1577. Elizabeth was born about 1556 in Cranston Riddell, Dalkeith, Edinburghshire, Scotland; died in May 1622. [Group Sheet] [Family Chart]

Notes:

He acquired Culzean from his brother in 1622.
John, succeeded to Culzean, ancestor of tenth Earl of Cassillis.
Alexander of Craigoch and Kilhenzie, m. Anna Crawford.
Major Thomas of Baltersan.
James.
Marion; m. James Kennedy of Girvanmains.
Margaret.
Agnes

Family/Spouse: Agnes KENNEDY. Agnes was born about 1596 in Ardmillan, Girvan, Ayrshire, Scotland; died in UNKNOWN. [Group Sheet] [Family Chart]